Tag Archives: tumour

Solid tumour CAR-T cells engineered with fusion proteins targeting PD-L1 for localized IL-12 delivery

Solid tumour CAR-T cells engineered with fusion proteins targeting PD-L1 for localized IL-12 delivery

Cell lines The mouse prostate cancer cell line PTEN−/− Kras (PTEN–Kras) derived from 10-week K-ras G12D;PTEN deletion mutant prostate cells was a kind gift from David Mulholland (The Icahn School of Medicine at Mount Sinai)42. The Ras/Myc transformed prostate cancer line, RM9, was a kind gift from Timothy C. Thompson (MD Anderson Cancer Centre) and has been previously described45. ID8, …

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Flint mum says baby’s brain tumour symptoms dismissed as colic

Flint mum says baby’s brain tumour symptoms dismissed as colic

Antonia Matthews and Danielle HerbertBBC Wales Corinne Wardle Molly had nine hours of surgery, aged just 12 weeks, when the tumour was finally discovered A mum whose baby daughter was diagnosed with a brain tumour, after her symptoms were dismissed as colic and reflux for more than two months, is calling for better awareness of the condition. Newborn Molly appeared …

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Cancer breakthrough: Scientists discover protein that could stop tumour growth in the pancreas |

Cancer breakthrough: Scientists discover protein that could stop tumour growth in the pancreas |

Scientists have made a promising discovery that could transform the treatment of pancreatic cancer, one of the deadliest forms of the disease. Researchers at the Institute of Cancer Research in London have identified a protein called SPP1 that plays a key role in the aggressive spread of pancreatic ductal adenocarcinoma (PDAC), the most common form of pancreatic cancer. By blocking …

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Optimo DJ JD Twitch dies after being diagnosed with brain tumour

Optimo DJ JD Twitch dies after being diagnosed with brain tumour

Getty Images Keith McIvor, also known as JD Twitch, started the Optimo Espacio club night at Sub Club in 1997 Keith McIvor, one half of Glasgow club duo Optimo, has died aged 57. Known by the stage name JD Twitch, he was diagnosed with an untreatable brain tumour earlier this year. In a statement posted on social media his fellow …

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‘My runny nose turned out to be a brain tumour’ says Warrington man

‘My runny nose turned out to be a brain tumour’ says Warrington man

SWNS Kieran Shingler and his girlfriend, Abbie Henstock A man who thought he was suffering with the flu was given 12 months to live when it was revealed he had a brain tumour. Kieran Shingler, 26, from Warrington, initially dismissed his symptoms which included a headache, sore throat, and runny nose back in 2022. However, when his condition worsened, he …

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Father-of-two with inoperable brain tumour warns others about the strange symptom he ignored

Father-of-two with inoperable brain tumour warns others about the strange symptom he ignored

A fit and healthy father-of-two received a devastating brain tumour diagnosis after a bizarre symptom triggered a violent seizure—a lasting smell of bleach.  Sam Suriakumar, 40, from London, didn’t think much of it the first time he smelled the strong ammonia-like chemical, assuming that his wife, Sindu, had just cleaned the bathroom.  ‘The smell of ammonia, bleach or some sort …

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‘I wasn’t drunk, it was a brain tumour’

‘I wasn’t drunk, it was a brain tumour’

Stuart Maisner BBC News, South East Brain Tumour Research John Starns is raising awareness for Brain Cancer Research A man who said he appeared drunk but was actually suffering from a brain tumour is helping to raise awareness of the disease. John Starns, from Sutton Valence, Kent, was initially told he had vertigo but when there was no improvement with …

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I thought I was suffering a menopause symptom almost all women get… in fact, it was an inoperable brain tumour

I thought I was suffering a menopause symptom almost all women get… in fact, it was an inoperable brain tumour

A mother-of-one who dismissed her forgetfulness as a menopause symptom was devastated to be told she had an inoperable brain tumour. April Tate, 52, from Burntisland in Fife, first became concerned in 2018 when she forgot a child’s name while working as a childminder.  Believing it was hormonal, she mentioned it during a routine GP phone call—only to be asked …

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Contraception used by thousands increases risk of brain tumour, study finds

Contraception used by thousands increases risk of brain tumour, study finds

Women on a widely–used contraceptive jab are three–and–a–half times more likely to suffer a potentially–fatal brain tumour, a study shows. It’s the third major investigation in just over a year to show the jab raises the risk of a meningioma, the most common type of tumour in the brain, in those on it for 12 months or more. Around 10,000 …

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