Tag Archives: trisomy

Myocardial reprogramming by HMGN1 underlies heart defects in trisomy 21

Myocardial reprogramming by HMGN1 underlies heart defects in trisomy 21

Animal models All animals used in this study were handled in accordance with protocols approved by the Institutional Animal Care and Use Committees (IACUC) at the University of California San Francisco. All protocols were conducted in accordance with guidelines from the National Institutes of Health Guide for the Care and Use of Laboratory Animals. Wild-type C57Bl6/J (Stock:000664) transgenic mice were …

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