Tag Archives: Tissue

Large-scale visualization of α-synuclein oligomers in Parkinson’s disease brain tissue

Large-scale visualization of α-synuclein oligomers in Parkinson’s disease brain tissue

Autofluorescence suppression and high-sensitivity microscopy reveals nanoscale assemblies in human brain tissue An overview of the ASA–PD pipeline is shown in Fig. 1. In brief, the aim is to capture spatial data over the entire scale of structure sizes most critical in PD, from individual cells to small aggregates (Fig. 1a). Detailed descriptions of the sample preparation steps are described …

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Explainer | Gold thread acupuncture uses gold wires for pain relief, could cause infections, tissue damage

Explainer | Gold thread acupuncture uses gold wires for pain relief, could cause infections, tissue damage

A bizarre therapy involving thin golden threads embedded in people’s bodies during acupuncture treatment has garnered significant attention after media exposure revealed X-ray images of South Korean patients showing hundreds of these thread strands. One patient, a 65-year-old woman diagnosed with osteoarthritis of the knee – a degenerative joint condition that causes pain and stiffness – shared her experience with …

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Divergent evolutionary strategies pre-empt tissue collision in gastrulation

Divergent evolutionary strategies pre-empt tissue collision in gastrulation

Experimental animals and embryo collection D. melanogaster embryos were collected on apple juice agar plates with yeast paste at 22 °C or at the temperatures indicated below. Laboratory cultures of M. abdita (Sander strain) were maintained as described52. M. abdita embryos were collected on apple juice agar plates with fish food paste at 25 °C. The laboratory cultures of C. riparius (Bergstrom …

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Tiny 3D-Printed Device Supercharges Tissue Engineering With Unprecedented Precision

Tiny 3D-Printed Device Supercharges Tissue Engineering With Unprecedented Precision

The Suspended Tissue Open Microfluidic Patterning, or STOMP device, is small enough to fit on a fingertip, and is expected to advance human tissue modeling for research on a variety of complex diseases. Credit: University of Washington The device is compact enough to rest on a fingertip and is compatible with current tissue-engineering technology. A newly developed 3D-printed device offers …

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Single-cell DNA methylome and 3D genome atlas of human subcutaneous adipose tissue

Single-cell DNA methylome and 3D genome atlas of human subcutaneous adipose tissue

Multimodal profiling of human SAT cell types To investigate the cell-type-level epigenomic landscape of human SAT, we profiled DNA methylation, chromatin conformation and gene expression on nuclei isolated from SAT biopsies from Finnish females (Fig. 1 and Supplementary Note 1.1). We used snm3C-seq to simultaneously profile single-cell-level DNA methylation and chromatin conformation of nuclei isolated from five SAT biopsies (see …

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Dolphins RB De’Von Achane will miss time with soft tissue lower body injury

Dolphins RB De’Von Achane will miss time with soft tissue lower body injury

Running back De’Von Achane was one of 28 players who were inactive for the Dolphins in their 24-17 victory over the Lions on Saturday. Dolphins coach Mike McDaniel told reporters after that game that Achane has a soft-tissue lower-body injury that will keep him out between “days and weeks.” McDaniel, though, added that he’s not concerned about Achane’s availability for …

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'Missing link' to Alzheimer's disease found in study of human brain tissue – AOL.com

‘Missing link’ to Alzheimer’s disease found in study of human brain tissue  AOL.com Could Lithium Explain — and Treat — Alzheimer’s Disease?  Harvard Medical School Research on reversing Alzheimer’s reveals lithium as potential key  The Washington Post Scientists say it may be possible to protect aging brains from Alzheimer’s with an old remedy — lithium  CNN Alzheimer’s Breakthrough: Lithium Reverses Memory Loss in Mice  ScienceAlert …

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