Tag Archives: Therapeutic

Preliminaries A calligraphic letter \({\mathcal{X}}\) indicates a set, an italic uppercase letter X denotes a graph, uppercase X denotes a matrix, lowercase x denotes a vector, and a monospaced letter X indicates a tuple. Uppercase letter \({\mathsf{X}}\) indicates a random variable, and lowercase letter \({\mathsf{x}}\) indicates its corresponding value; bold uppercase \({\boldsymbol{\mathsf{X}}}\) denotes a set of random variables, and lowercase …

Migration of transplanted allogeneic myeloid cells into the brain following systemic hematopoietic stem and progenitor cells transplantation (HCT) holds great promise as a therapeutic modality to correct genetic deficiencies in the brain such as lysosomal storage diseases.1–3 However, the toxic myeloablation required for allogeneic HCT can cause serious, life-threatening side effects limiting its applicability. Moreover, transplanted allogeneic myeloid cells are …