There are at least four distinct subtypes of autism, a new study finds, helping to explain the various trajectories of individuals on the spectrum and offering a path toward more targeted treatments. Researchers grouped over 5,000 children ages 4 to 18 with autism based on more than 230 traits like social interactions, repetitive behaviors and developmental milestones to arrive at …
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Four autism subtypes map onto distinct genes, traits
Autism has long been seen as a single—if highly heterogeneous—condition. But rather than one continuous spectrum, there are distinct autism subtypes, each tied to its own genetic signature, a new study suggests. The research, published 9 July in the journal Nature Genetics, connects genetic differences to specific patterns in how autism traits appear, supporting the notion that there are “many …
Read More »Four Distinct Autism Subtypes Identified
By leveraging a person-centered computational approach to phenotypic data from more than 5000 children with autism spectrum disorder (ASD), researchers have identified four biologically and clinically distinct subtypes of autism and their underlying genetic signals. These four subtypes are: Social and Behavioral Challenges, Mixed ASD with Developmental Delay, Moderate Challenges, and Broadly Affected. “It’s important for families to have groups …
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