Summary: Scientists have found that people with multiple sclerosis (MS) have a distinctly imbalanced oral microbiome—marked by a loss of beneficial bacteria and a rise in inflammation-linked microbes. Using advanced genetic and metabolic profiling, researchers revealed that saliva from MS patients also had lower levels of hypotaurine, a molecule that supports antioxidant defense and nerve health. These microbial and metabolic …
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First Signs of Multiple Sclerosis Found Years Before Symptoms
Summary: Researchers have traced the earliest stages of multiple sclerosis (MS), showing that the immune system begins attacking the brain up to seven years before diagnosis. By analyzing over 5,000 blood proteins, they identified molecular signs of damage to myelin—the protective sheath around nerve fibers—long before symptoms emerge. Key biomarkers such as IL-3 and MOG reveal a two-stage attack, first …
Read More »Breakthrough compounds may reverse nerve damage caused by multiple sclerosis
Multiple sclerosis (MS) is a long-term autoimmune condition that affects over 2.9 million people around the world. In MS, the immune system mistakenly attacks the myelin sheath, a protective layer that insulates nerve fibers. This damage interrupts communication between the brain and body, leading to symptoms such as numbness, tingling, vision problems, and paralysis. Although existing treatments can help reduce …
Read More »Compound Could Repair Nerve Damage in Multiple Sclerosis
Summary: Researchers have identified two compounds capable of repairing the protective myelin sheath damaged by multiple sclerosis, a major advance toward reversing nerve injury rather than just slowing it. The lead compound, K102, not only promotes remyelination but also balances immune function—key for long-term neurological recovery. In animal and cell studies, it restored myelin-producing cells and showed strong potential for …
Read More »ECTRIMS 2025: Frexalimab helps control MS for 2.5 years in study – Multiple Sclerosis News Today
ECTRIMS 2025: Frexalimab helps control MS for 2.5 years in study Multiple Sclerosis News Today Source link
Read More »Autoimmune response to C9orf72 protein in amyotrophic lateral sclerosis
Study approval All participants provided written informed consent for participation in the study. Ethical approval was obtained from the Institutional Review Boards at La Jolla Institute for Immunology (protocol numbers VD-124, VD-118, VD-155 and VD-171), Massachusetts General Hospital (protocol number 2006P000982), Emory University (protocol number CR003-IRB00078771), University of California, Irvine (protocol number 20163191), National Institutes of Health (protocol number 17N0131), …
Read More »ECTRIMS 2025: Updated McDonald criteria enable more MS diagnoses – Multiple Sclerosis News Today
ECTRIMS 2025: Updated McDonald criteria enable more MS diagnoses Multiple Sclerosis News Today Implementation of the 2024 revision of the McDonald criteria for multiple sclerosis Nature MS guidelines updated with new red flags Medical Republic What to Know: New MS Diagnostic Criteria National Multiple Sclerosis Society New Criteria Could Improve Speed, Accuracy of MS Diagnosis Medscape Source link
Read More »Diets improve health markers in MS, but don’t affect brain lesions – Multiple Sclerosis News Today
Diets improve health markers in MS, but don’t affect brain lesions Multiple Sclerosis News Today Source link
Read More »Getting vaccinated helps me protect myself and others with MS – Multiple Sclerosis News Today
Getting vaccinated helps me protect myself and others with MS Multiple Sclerosis News Today Source link
Read More »Multiple sclerosis research; kiss your dentist goodbye
On this week’s program, how government funding cuts and climate change are affecting people living with multiple sclerosis and health care experts working on a cure. From the personal struggles of patients to the fight for research breakthroughs, Dr. Joe Sirven and his guest explore what it will take to overcome these current obstacles. Guest: Then, drilling into conventional wisdom. …
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