Tag Archives: reprograms

Researchers at Trinity College Dublin have found that applying electrical currents to “macrophages,” a crucial type of immune cell, can reprogram them to reduce inflammation and promote faster healing in cases of disease or injury. This discovery points to a promising new treatment strategy, and the research team is continuing to study the mechanisms behind this effect. What Macrophages Do …

We adopted a five-step pipeline to identify candidates for enhancing neural repair with a streamlined path that could lead to human testing (Fig. 1a). Step 1 involves characterizing the transcriptomic state or ‘signature’ of a cell type that exhibits a beneficial biological effect. In this case, we used the transcriptome of corticospinal motor neurons that are capable of regeneration after SCI. …