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Gene Key to MS Immune Regulation Discovered
Summary: New research has identified the gene Egr-1 as a critical regulator of immune balance, offering hope for autoimmune disease therapies. In a mouse model of multiple sclerosis, loss of Egr-1 led to reduced regulatory T cell activity and heightened inflammation. The study showed Egr-1 directly boosts the expression of Foxp3, a protein essential for Treg cells, via the TGF-β …
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