Scientists have repaired a natural gateway into the brains of mice, allowing the clumps and tangles associated with Alzheimer’s disease to be swept away. After just three drug injections, mice with certain genes that mimic Alzheimer’s showed a reversal of several key pathological features. Within hours of the first injection, the animal brains showed a nearly 45 percent reduction in …
Read More »
Plastics are now everywhere, with tiny fragments found in several major organs of the human body, including the placenta. Given how easily the microscopic particles infiltrate our tissues, it’s vital that we learn exactly what kinds of risks they could pose to our health. Researchers have been busy studying the effects of microplastics in mini-replicas of organs, and in mice, …
Read More »
Summary: A new large-scale study shows that Alzheimer’s disease is marked by the erosion of epigenomic control, where brain cells lose the ability to maintain stable gene expression. Using a multi-region atlas of 3.5 million cells, researchers found that vulnerable cells in key memory regions such as the hippocampus suffer breakdowns in nuclear compartmentalization and lose their “epigenomic information.” This …
Read More »
COVID-19 could lead to a protein build-up similar to that seen in Alzheimer’s patients – not just in the brain, but also in the eyes, according to a new study. This may explain why ‘brain fog’, an umbrella term for issues with memory or cognition, is often reported as a symptom of COVID-19. In a new study led by Yale …
Read More »