Cell lines The mouse prostate cancer cell line PTEN−/− Kras (PTEN–Kras) derived from 10-week K-ras G12D;PTEN deletion mutant prostate cells was a kind gift from David Mulholland (The Icahn School of Medicine at Mount Sinai)42. The Ras/Myc transformed prostate cancer line, RM9, was a kind gift from Timothy C. Thompson (MD Anderson Cancer Centre) and has been previously described45. ID8, …
Read More »Solid tumour CAR-T cells engineered with fusion proteins targeting PD-L1 for localized IL-12 delivery
