Tag Archives: pain

New Drug Aims to Block Pain Without Addiction Risks

New Drug Aims to Block Pain Without Addiction Risks

Summary: Chronic pain affects millions, but opioid medications bring high risks of dependence and side effects. Researchers have now pinpointed specific neurons in the amygdala that make pain feel unpleasant, opening the door to drugs that ease suffering without shutting down normal sensation. With a new $12 million NIH grant, scientists are working to design small molecules that target these …

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The discovery of a gene for chronic pain could herald new treatments

The discovery of a gene for chronic pain could herald new treatments

CHRONIC PAIN wrecks the lives of more than 600m people around the world. One in five adults struggles with it. What causes it, however, is often a mystery. The prevailing hypothesis is that, after an injury, something goes wrong with the body’s pain receptors and the alarm system that reports injuries to the brain keeps ringing long after the body …

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SLC45A4 is a pain gene encoding a neuronal polyamine transporter

SLC45A4 is a pain gene encoding a neuronal polyamine transporter

Study Population The UKB is a prospective cohort study that has collected extensive phenotypic and genetic data from approximately 500,000 participants across the United Kingdom21,45. All of the participants provided written informed consent. Phenotype description and assessment Phenotypes were defined using the ‘Experience of Pain’ UKB self-assessment questionnaire data under project ID 49572. This is part of the online UKB …

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5 of the most common reasons Utah residents suffer from back pain

5 of the most common reasons Utah residents suffer from back pain

Back pain is one of the most common health complaints in the U.S. According to research from PubMed Central, lower back pain affects about 84% of people at some point in their lives, and around 23% go on to develop chronic pain. It can come on suddenly after an awkward movement or build up gradually until it starts interfering with …

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Tonix Pharma’s Drug Gets FDA Nod For Chronic Pain Condition, First New Therapy In Over 15 Years

Tonix Pharma’s Drug Gets FDA Nod For Chronic Pain Condition, First New Therapy In Over 15 Years

On Friday, the U.S. Food and Drug Administration (FDA) approved Tonix Pharmaceuticals Holding Corp.’s (NASDAQ:TNXP) Tonmya (cyclobenzaprine HCl sublingual tablets) for fibromyalgia in adults. Fibromyalgia is a chronic condition characterized by widespread musculoskeletal pain, fatigue, and other symptoms like sleep disturbances and cognitive difficulties. Tonmya is a non-opioid, once-daily bedtime analgesic with a unique sublingual (under the tongue) formulation that is …

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Pain took football away from Andrew Luck; what brought him back to Stanford?

Pain took football away from Andrew Luck; what brought him back to Stanford?

PALO ALTO, Calif. — He built his house on the water thinking he’d never leave. It was five minutes from the Indianapolis Colts’ practice facility. It’s where his kids would grow up, where he and his wife would ease into middle age. It’s where he imagined storing a Super Bowl ring or two. Life was simpler then, “a binary existence” …

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Small change to how you walk may help relieve osteoarthritis pain – AOL.com

Small change to how you walk may help relieve osteoarthritis pain  AOL.com How small changes in walking technique may help treat knee osteoarthritis  Medical Xpress One small walking adjustment could delay knee surgery for years  ScienceDaily This small walking style change can delay knee surgery for years, study finds  The Independent Personalized Gait Retraining Beneficial for Medial Compartment Knee OA  Endocrinology Advisor Source link

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‘Genuinely healing’ after 13 years of endometriosis pain

‘Genuinely healing’ after 13 years of endometriosis pain

@bindisueirwin / Instagram Bindi Irwin says she’s on the mend after 13 years of endometriosis pain Australian conservationist and TV personality Bindi Irwin has said she is “genuinely healing” after suffering years of pain from endometriosis and called for greater understanding of the condition. Irwin, who first revealed her decade-long struggle with the disease in 2023, said in an update, …

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