Tag Archives: obesity

Proposed acquisition to add four highly differentiated clinical-stage incretin and amylin programs to Pfizer’s pipeline Transaction valued at $47.50 per Metsera share in cash upon closing, for an initial enterprise value of $4.9 billion with a CVR of up to $22.50 per share in additional payments Pfizer to host a public webcast at 8 am EDT today NEW YORK–(BUSINESS WIRE)– …

1. Reduced hunger Glucagon-like peptide-1 (GLP-1) receptor agonists such as semaglutide (Wegovy) and tirzepatide (Mounjaro) have been shown to help people living with obesity lose weight. By mimicking the action of a hormone called GLP-1, they reduce appetite and feelings of hunger, slow the release of food from the stomach and increase feelings of fullness after eating. “It works by …

Orforglipron, an oral GLP-1 agonist, helped patients with obesity lose up to 11% of their body weight in a major trial, offering a promising alternative to injectable therapies. (Artist’s concept). Credit: Stock The results of this landmark trial are particularly significant, as oral therapies for obesity could improve both access to and affordability of treatment; moreover, many patients prefer oral …

Why Obesity Is Killing American Men  The New York Times Source link

Lilly’s Obesity Pill Will Have Far-Reaching Effect, Doctors Say  Bloomberg Lilly trial shows weight loss with experimental pill flattens over time  CNBC Lilly’s oral GLP-1, orforglipron, demonstrated meaningful weight loss and cardiometabolic improvements in complete ATTAIN-1 results published in The New England Journal of Medicine  Eli Lilly and Company Daily weight loss pill can help cut body weight by a fifth, trial shows  The …

A sign with the company logo sits outside of the headquarters of Eli Lilly in Indianapolis, Indiana, on March 17, 2024. Scott Olson | Getty Images Eli Lilly on Wednesday said its experimental pill outperformed Novo Nordisk‘s own oral drug in the first head-to-head study comparing the two medicines in patients with Type 2 diabetes.  The late-stage study comes as Eli …

Courcoulas, A. P. et al. Long-term outcomes of medical management vs bariatric surgery in type 2 diabetes. JAMA 331, 654–664 (2024). Article  PubMed  PubMed Central  Google Scholar  Mingrone, G. et al. Bariatric–metabolic surgery versus conventional medical treatment in obese patients with type 2 diabetes: 5 year follow-up of an open-label, single-centre, randomised controlled trial. Lancet 386, 964–973 (2015). Article  PubMed  …

WHO backs weight-loss drugs for obesity and urges change in mindset  Reuters WHO backs weight-loss drugs for obesity  K24 Digital WHO backs weight-loss drugs, urges cheap generics  daily-sun.com Source link

The number of obese school-aged children has exceeded the number of underweight children globally, according to a new report released by UNICEF. This is the first time obesity has overtaken undernourishment as the leading form of malnutrition among children aged five to 19, according to the report released on Wednesday. Today, “when we talk about malnutrition, we are no longer …

With nearly one in eight people around the world living with obesity in 2022, the disease has more than doubled among adults and quadrupled among adolescents over the past three decades. This complex and chronic condition of excessive body fat increases the risk of non-communicable diseases such as diabetes, heart disease and cancer. Yet despite its surge in industrialized populations, …