Tag Archives: Neurons

Summary: Scientists have discovered specialized IC-encoder neurons that make the brain “see” illusions, such as squares or triangles that aren’t truly there. These neurons receive top-down instructions from higher brain areas and then fill in missing contours in the visual cortex, actively constructing what we perceive. Experiments showed that stimulating these neurons alone could reproduce the same brain activity as …

Mice This study was performed in accordance with FELASA recommendations and with European Union and German guidelines. The experiments were approved by the local ethics committee on animal experiments (Landesamt für Natur, Umwelt und Verbraucherschutz Nordrhein-Westfalen). Mice were housed in groups of up to five animals per cage and supplied with standard pellet food and water ad libitum with a …

Isolation of nuclei from post-mortem brain tissue Batch 1 nuclei (BA10 region, frozen tissue) were isolated according to a protocol adapted from a previous study18, performed entirely at 4 °C or on ice. In brief, tissue was homogenized (700 µl homogenization buffer: 320 mM sucrose, 5 mM CaCl2, 3 mM Mg(CH3COO)2, 10 mM Tris-HCl pH 7.8, 0.1 mM EDTA pH 8.0, 0.1% IGEPAL CA-630, 1 mM β-mercaptoethanol, 0.4 U µl−1 recombinant RNase …

Summary: Researchers studying people with epilepsy have discovered that nerve cells in the medial temporal lobe coordinate their firing with slow brain waves to encode and retrieve memories. This synchronization, known as theta-phase locking, occurs at one to ten cycles per second and is active during both learning and recall. The strength of this rhythm during memory formation did not …

Surprising Alzheimer’s breakthrough: Sugar in neurons might be the missing link  PsyPost Source link

Summary: New research has uncovered that neurons store their own glycogen, acting as “backup batteries” to keep the brain functioning during energy stress. Using worms and advanced biosensors, scientists found that neurons can tap into glycogen reserves, especially when oxygen or mitochondrial function is limited. This metabolic flexibility, termed “glycogen-dependent glycolytic plasticity,” shows neurons are more self-sufficient than previously believed. …