Tag Archives: Nature

Depriving brain tumours of an amino acid could enhance chemotherapy  Nature Source link

With one riddle solved, the team focused on another: how those lumps got there. Turning back the clock, they concluded that the lumps likely arrived as giant asteroids or other rocky material that struck Mars during the early solar system, generating those oceans of magma as they drove deep into the mantle, bringing with them fragments of crust and mantle. …

Rocky material that impacted Mars lies scattered in giant lumps throughout the planet’s mantle, offering clues about Mars’ interior and its ancient past. What appear to be fragments from the aftermath of massive impacts on Mars that occurred 4.5 billion years ago have been detected deep below the planet’s surface. The discovery was made thanks to NASA’s now-retired InSight lander, …

Competing interests M.J.F. has served as a paid consultant with Minovia Therapeutics (last in 2021) and Imel Therapeutics (last in 2022), and has served as a preclinical stage research collaborator with Minovia Therapeutics (last in 2022) and Imel Therapeutics (last in 2022). M.J.F is also engaged with biopharma companies involved in mitochondrial disease therapeutic preclinical and/or clinical-stage development, including as …

Snapshot optical image generation process The snapshot optical generation procedure includes two parts: the digital encoder and the optical generative model. For image generation of MNIST, Fashion-MNIST, Butterflies-100 and Celeb-A, the digital encoder architecture that we selected is a variant of the multi-layer perceptron54, which contained Ld fully connected layers, each of which was followed by a subsequent activation function …

We’ve heard of GMOs, but this is ridiculous. Scientists at the Medical Research Council’s Laboratory of Molecular Biology say they’ve engineered a bacteria whose genetic code is more efficient than any other lifeform on Earth. They call their creation “Syn57,” a bioengineered strain of E. coli — yes, the same bad boy that can make you extremely sick if you …

STING induces ZBP1-mediated necroptosis independently of TNFR1 and FADD  Nature Source link

Protein expression and purification In Figs. 1–4 and 5d, we measured EYFP with the mutations S2insL/S65G/V68L/S72A/T203Y/H231L of avGFP, with an additional 6x His tag on the N-terminus (the full amino acid sequence is given at the end of this section). The protein was expressed using a pET vector constructed using HiFi assembly from Addgene plasmids 78466 and 29653. The resulting vector …

Image by Getty / Futurism “Go outside” or “touch grass” are common rejoinders deployed in online arguments these days. And, at least for those of us whose brains have probably melted from spending too much time on an app where said arguments take place, it turns out it’s pretty sound advice. As the New York Times reports, there’s a growing …

A baby benefits from personalized gene editing in the clinic  Nature Source link