Tag Archives: modulator

Genome-scale CRISPR screens identify PTGES3 as a direct modulator of androgen receptor function in advanced prostate cancer

Genome-scale CRISPR screens identify PTGES3 as a direct modulator of androgen receptor function in advanced prostate cancer

Ethical statement All experiments detailed in this paper were performed in compliance with the Institutional Review Board and the Institutional Animal Care and Use Committee (IACUC) at the University of California, San Francisco and Fred Hutchinson Cancer Center. All animal studies were conducted in compliance with UCSF IACUC guidelines with protocol number AN182067. Cell lines and reagents Cell lines LNCaP, …

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