Neural organoids were differentiated from iPSC-derived Neural Progenitor Cells (NPC) for up to 14 weeks and characterized throughout development (Fig. 1a). Gene expression of synaptic plasticity markers was quantified from week 0 to week 12. Calcium signaling development was analyzed from week 2 to week 14. Finally, electrical activity was characterized by High-Density Microelectrode Arrays (HD-MEAs) over two independent time periods, from …
Read More »Human neural organoid microphysiological systems show the building blocks necessary for basic learning and memory
