Tag Archives: Mice

Animal models The following mouse lines were used: C57BL/6J mice (The Jackson Laboratory, line 000664), C57BL/6 aged mice (National Institutes of Aging) and B6;129-Gt(ROSA)26Sortm1(CAG-cas9*,-EGFP)Fezh/J (The Jackson Laboratory, line 024857). All studies were done in young (2–3 months) or aged (18–22 months) male mice that were not involved in any previous procedures. The numbers of mice used to result in statistically significant differences …

Chinese scientists have found a way to turn human stem cells into dopamine-producing brain cells, transplanting them into mice and helping reduce depressive behaviour and boost pleasure. When the engineered neuron-like cells were grafted into depression-model mice, they helped lessen symptoms like anxiety and resignation while increasing feelings of enjoyment. The development has the potential to be employed as a …

On August 20, 2025, Russia will launch the Bion-M No. 2 biosatellite atop a Soyuz-2.1b rocket from the Baikonur Cosmodrome in Kazakhstan, marking a key step in studying the effects of spaceflight on living organisms. As reported by Space.com, the spacecraft will carry 75 mice, over 1,000 fruit flies, and other biological specimens for a 30-day mission in space, exposing …

Russia is preparing to loft a “miniature mouse hotel” into space. An inside view of the rodent-holding unit. (Image credit: Roscosmos) The Bion-M No. 2 biosatellite is being readied for its planned Aug. 20 launch atop a Soyuz-2.1b rocket from Baikonur Cosmodrome in Kazakhstan. Onboard are 75 mice and other specimens to be exposed to 30 days of radiation before …

SALT LAKE CITY — Researchers at the University of Utah say new weight loss drugs pose new questions about what happens to muscle mass and strength when people slim down and lose more than just fat. The scientists are starting to get answers to those questions by studying the effects of semaglutide — the active ingredient in the popular weightloss …

A study published in 2022 found a tenuous but plausible link between picking your nose and an increased risk of developing dementia. In cases where picking at your nose causes internal tissue damage, critical species of bacteria have a clearer path to the brain, which responds to their presence in ways that resemble signs of Alzheimer’s disease. There are numerous …

A study published in 2022 found a tenuous but plausible link between picking your nose and an increased risk of developing dementia. In cases where picking at your nose causes internal tissue damage, critical species of bacteria have a clearer path to the brain, which responds to their presence in ways that resemble signs of Alzheimer’s disease. There are numerous …

The worry that breast cancer may someday return is a troubling source of anxiety for many survivors of the disease. It’s understandable why, since most relapses and metastatic cancers (cancers that have spread) aren’t started by new tumours. Rather, they’re caused by sleeper cancer cells that suddenly awaken. These “dormant” cancer cells usually colonise places such as the lungs or …

We may have new hope in the battle against Alzheimer’s disease. Researchers have found that lithium levels in the brain are closely linked to the condition, and that lithium supplements can reverse Alzheimer’s-like memory loss in mice. Led by a team from Harvard Medical School, the researchers wanted to investigate previous links that have been made between exposure to metals …

A slice from a normal human brain (left, artificially coloured) contrasts with a slice from the brain of a person with Alzheimer’s disease.Credit: Jessica Wilson/Science Photo Library Replenishing the brain’s natural stores of lithium can protect against and even reverse Alzheimer’s disease, suggests a paper published1 today in Nature. The paper reports that analyses of human brain tissue and a …