Immune-competent LOC mimics small airway cell composition The immune-competent LOC model of the small airway comprises a three-dimensional (3D), perfusable microvascular network underneath a mature, differentiated airway epithelium at an air–liquid interface (ALI). The 3D microvascular network provides a unique advantage in that it is comprised of both endothelial cells and fibroblasts in a hydrogel matrix, in which interstitial immune …
Read More »An immune-competent lung-on-a-chip for modelling the human severe influenza infection response
