Tag Archives: inhibition

How the Brain Balances Excitation and Inhibition

How the Brain Balances Excitation and Inhibition

Inhibitory neurons have “often been ascribed support roles,” said Annabelle Singer, a neuroscientist and neuroengineer at the Georgia Institute of Technology and Emory University. That’s likely because it’s simply easier to study excitatory neurons. For example, an excitatory place cell in the hippocampus can fire when an animal is in a particular location. When this happens, its excitation of other …

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Selective presynaptic inhibition of leg proprioception in behaving Drosophila

Selective presynaptic inhibition of leg proprioception in behaving Drosophila

Proske, U. & Gandevia, S. C. The proprioceptive senses: their roles in signaling body shape, body position and movement, and muscle force. Physiol. Rev. 92, 1651–1697 (2012). Article  CAS  PubMed  Google Scholar  Tuthill, J. C. & Azim, E. Proprioception. Curr. Biol. 28, R194–R203 (2018). Article  CAS  PubMed  Google Scholar  Azim, E. & Seki, K. Gain control in the sensorimotor system. …

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IL6 genetic perturbation mimicking IL-6 inhibition is associated with lower cardiometabolic risk

IL6 genetic perturbation mimicking IL-6 inhibition is associated with lower cardiometabolic risk

GBD Causes of Death Collaborators. Global burden of 288 causes of death and life expectancy decomposition in 204 countries and territories and 811 subnational locations, 1990–2021: a systematic analysis for the Global Burden of Disease Study 2021. Lancet 403, 2100–2132 (2024). Goh, R. S. J. et al. The burden of cardiovascular disease in Asia from 2025 to 2050: a forecast …

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