Tag Archives: Influenza

A vaccine central in A(H5) influenza antigenic space confers broad immunity

A vaccine central in A(H5) influenza antigenic space confers broad immunity

Phylogenetic tree construction All available A(H5) HA nucleotide sequences and accompanying metadata were downloaded from the GISAID Data Science Initiative60 and the Bacterial and Viral Bioinformatics Resource Center (BV-BRC)61 databases on 5 May 2023. The HA sequences of three antigens present in-house (A/Vietnam/3218/2004, A/duck/Hong-Kong/1091/2011 and A/eurasian-wigeon/Netherlands/EMC-3/2014), which were not yet available through the above mentioned databases at the time, were …

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H3N2 influenza spreads rapidly in Delhi, northern India – DW – 09/28/2025

H3N2 influenza spreads rapidly in Delhi, northern India – DW – 09/28/2025

Northern India, in particular the Delhi metropolitan region, is experiencing a significant spike in infections with the H3N2 strain of influenza this autumn. There are about 46 million people in the conurbation around the Indian capital, which extends across many neighboring towns and districts in the states of Haryana, Uttar Pradesh and Rajasthan. According to a survey by the community-based social media …

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Recommendations announced for influenza vaccine composition for the 2026 southern hemisphere influenza season

Recommendations announced for influenza vaccine composition for the 2026 southern hemisphere influenza season

The World Health Organization (WHO) today announced its recommendations for the viral composition of influenza vaccines for use in the 2026 influenza season in the southern hemisphere. The announcement was made at an Information Meeting after a 4-day Consultation on the Composition of Influenza Virus Vaccines.   Given the constantly evolving nature of influenza viruses, regular updates to vaccine composition …

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Pediatric Influenza-Associated Encephalopathy and Acute Necrotizing Encephalopathy — United States, 2024–25 Influenza Season

Pediatric Influenza-Associated Encephalopathy and Acute Necrotizing Encephalopathy — United States, 2024–25 Influenza Season

Amara Fazal, MD1; Elizabeth J. Harker, MPH1; Varsha Neelam, MPH1; Samantha M. Olson, MPH1; Melissa A. Rolfes, PhD1; Katie Reinhart, PhD1; Krista Kniss, MPH1; Aaron Frutos, PhD1,2; Jerome Leonard, MD1,2; Carrie Reed, DSc1; Vivien G. Dugan, PhD1; Haytham Safi, MD3; Theresa M. Dulski, MD3,4; Adrianna Stanley-Downs, MD5; Aaliya Bhatti, MPH5; Isaac Armistead, MD6; Suchitra Rao, MBBS7; Carola Torres-Diaz, MPH8; Ashlin …

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An immune-competent lung-on-a-chip for modelling the human severe influenza infection response

An immune-competent lung-on-a-chip for modelling the human severe influenza infection response

Immune-competent LOC mimics small airway cell composition The immune-competent LOC model of the small airway comprises a three-dimensional (3D), perfusable microvascular network underneath a mature, differentiated airway epithelium at an air–liquid interface (ALI). The 3D microvascular network provides a unique advantage in that it is comprised of both endothelial cells and fibroblasts in a hydrogel matrix, in which interstitial immune …

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Prevention and Control of Seasonal Influenza with Vaccines: Recommendations of the Advisory Committee on Immunization Practices — United States, 2025–26 Influenza Season

Prevention and Control of Seasonal Influenza with Vaccines: Recommendations of the Advisory Committee on Immunization Practices — United States, 2025–26 Influenza Season

Recommendations for Influenza Vaccination for the 2025–26 Season Routine annual influenza vaccination of all persons aged ≥6 months who do not have a contraindication to vaccination continues to be recommended. Information on timing, selection, administration, and contraindications and precautions follows. Timing of Vaccination For most persons who require only 1 dose of influenza vaccine for the season, vaccination should ideally …

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ACOG Releases Updated Maternal Immunization Guidance for COVID-19, Influenza, and RSV

ACOG Releases Updated Maternal Immunization Guidance for COVID-19, Influenza, and RSV

Washington, D.C.—Today, the American College of Obstetricians and Gynecologists (ACOG) released updated clinical guidance regarding vaccination during pregnancy against COVID-19, influenza, and RSV. The three guidance documents, all of which recommend maternal immunization, lay out the full body of current scientific evidence that underscores the safety and benefits of choosing to be vaccinated against these respiratory conditions during pregnancy. “It …

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