Tag Archives: Immune

Researchers at UT Southwestern have uncovered a surprising way in which tumors exploit the body’s own immune system to grow unchecked. Their findings reveal a hidden interaction between a hormone and an immune receptor that switches cancer-fighting cells into cancer-supporting ones. Credit: Shutterstock A hormone-receptor interaction weakens immunity. Targeting it could fight cancer. Scientists at UT Southwestern Medical Center have …

Immunotherapy vaccine attacks cancer cells A virus that infects the humble black-eyed pea plant is showing great promise as a low-cost, potent cancer immunotherapy—thanks to researchers at the University of California San Diego. The team led by chemical and nano engineers just published their study in Cell Biomaterials, showing how the cowpea mosaic virus (CPMV), unlike other plant viruses, is …

A rare genetic condition that once looked like a weakness has revealed a hidden strength: immunity against nearly all viruses. Credit: Shutterstock Some people carry a rare mutation that makes them resistant to viruses. Now scientists have copied that effect with an experimental mRNA therapy that stopped both flu and COVID in animal trials — raising hopes for a universal …

Mice The mice used in this study were housed in pathogen-free facilities at the University of Chicago and Stanford University. All mice were housed in positively pressurized, individually ventilated cage racks and changed in biological safety cabinets. Cage supplies were sanitized using hot water (82 °C). Bedding and shredded-paper enrichment were autoclaved and cages were provided with irradiated food. Reverse Osmosis …

As winter wraps its chilly arms around us, many of us instinctively reach for our woolly scarves, vitamin C tablets, and that ever-comforting glass of mulled wine by the fire. It’s the season of boosting immunity, dodging cold viruses, and doing our best not to catch whatever bug the kids brought home from school. But here’s the twist: while we’re …

Psoriasis Breakthrough: Scientists Restore Immune Balance Without Harsh Side Effects  SciTechDaily Source link

Summary: A fading sense of smell may be one of the earliest warning signs of Alzheimer’s disease, and new research reveals why. Scientists found that microglia, immune cells in the brain, mistakenly remove nerve fibers connecting the locus coeruleus and olfactory bulb—two regions essential for processing odors. This immune-driven pruning occurs when hyperactive neurons display altered membranes, marking them as …

Cancer-fighting vaccine prompts immune response for some patients  Euronews.com Pancreatic cancer vaccine prevents recurrence in Phase 1 clinical trial  NBC News Off-the-shelf vaccine shows promise in preventing cancers returning, study finds  The Guardian Lymph node-targeted, mKRAS-specific amphiphile vaccine in pancreatic and colorectal cancer: phase 1 AMPLIFY-201 trial final results  Nature The 6 signs of pancreatic cancer to never ignore  The Independent Source link

Some Brains Stay Sharp Thanks to a Plaque Eating Immune Cell That Fights Alzheimer’s  SciTechDaily Enhanced brain immune cells may combat Alzheimer’s  drugdiscoverytrends.com Study Finds Boosting ACE in Microglia May Protect Against Alzheimer’s in Mice  geneonline.com Preclinical Study: Enzyme Could Help Treat Alzheimer’s Disease  Cedars-Sinai Source link

Varki, A. et al. Essentials of Glycobiology 3rd edn (Cold Spring Harbor Laboratory Press, 2015). Flynn, R. A. et al. Small RNAs are modified with N-glycans and displayed on the surface of living cells. Cell 184, 3109–3124 (2021). PubMed  PubMed Central  Google Scholar  Xie, Y. et al. The modified RNA base acp3U is an attachment site for N-glycans in glycoRNA. …