Tag Archives: Immune

A Trinity College Dublin team has discovered that electrical stimulation can reprogram macrophages to suppress inflammation and accelerate healing, opening the door to new therapeutic possibilities. Credit: Stock Trinity College Dublin scientists showed that electrical stimulation reprograms macrophages to reduce inflammation and boost healing. This breakthrough could lead to broad therapeutic uses. Researchers at Trinity College Dublin have shown that …

Summary: Alzheimer’s disease affects over 55 million people worldwide and has long been linked to toxic protein buildup and chronic inflammation in the brain. A new review shows that adaptive immune cells—T and B cells—also play a crucial role, sometimes worsening brain damage, sometimes offering protection. These findings suggest Alzheimer’s is not only a disease of plaques and tangles but …

Cancer sometimes gets the immune system to back off. A new study shows that a natural signal, a hormone, can tell certain white blood cells to slow down, which lets tumors grow. This finding points to a fresh target for treatment. It also helps explain why powerful cancer drugs work well for some people but not for others. Why this …

Pancreatic islets (artificially coloured) no longer secrete sufficient insulin in people with type 1 diabetes. Credit: Steve Gschmeissner/Science Photo Library In a medical first, researchers report that they have implanted CRISPR-edited pancreas cells into a person with type 1 diabetes. The cells pumped out sugar-regulating insulin for months — without the need for the recipient to take immune-dampening drugs, thanks …

Macrophages, which hoover up pathogens, have been implicated in the chronic inflammation that sets in with the march of time.Credit: Science Photo Library A newly discovered type of immune cell found in fat tissue seems to contribute to the chronic inflammation associated with ageing, according to preliminary data from mice — but other immune cells in fat help to keep …

Summary: A new study shows that chronic stress causes immune cells called neutrophils to leave bone marrow in the skull and collect in the brain’s protective membranes, where they contribute to depressive symptoms. In mice, blocking an immune “alarm” pathway reduced these cells and improved mood-related behaviors. The findings highlight how stress reshapes the brain’s immune environment and suggest why …

Summary: Researchers have uncovered a surprising link between gut immune cells and the brain in Alzheimer’s disease. In mice, antibody-producing B cells that normally reside in the gut were found migrating into brain border regions, influenced by chemokine signals from inflammatory brain cells. Feeding the animals a high-fiber diet restored gut immune balance and reduced frailty symptoms, even without lowering …

Your gut bacteria are far smarter than you might think. While we’ve long known that different foods can shift the balance of microbes in your digestive tract, new research reveals something even more fascinating: the same beneficial bacteria can completely change how they interact with your immune system1 based on what carbohydrates you feed them.  Source link

A new study shows that blocking one protein can reprogram immune cells to fight cancer more powerfully, offering hope for next-generation therapies. Credit: Shutterstock Blocking a single protein boosts T cell metabolism and tumor-fighting strength. The discovery could lead to next-generation cancer immunotherapies. Scientists have identified a strategy to greatly enhance the cancer-fighting abilities of the immune system’s T cells. …

Scientists in Japan have unveiled a revolutionary bacteria-based therapy that eradicates tumors without relying on the immune system, offering fresh hope for patients where standard treatments fail. Credit: Stock Two bacteria working in harmony show powerful antitumor effects. The approach could transform treatment for immunocompromised patients. A research team led by Professor Eijiro Miyako at the Japan Advanced Institute of …