Mice Tcf7flox/floxLef1flox/flox mice were generated by H.-H.X. (Center for Discovery and Innovation)20,61. Mb1Cre mice, Rag1−/− and CD45.1 mice were maintained on a C57BL/6 background and housed in specific pathogen-free conditions at the Australian National University (ANU) Bioscience Facility. Tcf7flox/floxLef1flox/flox mice were backcrossed at least six times onto the C57BL/6 background, then were subsequently crossed to Mb1Cre mice to generate conditional …
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Microglia–neuron crosstalk via Hex–GM2–MGL2 maintains brain homeostasis
These authors contributed equally: Takahiro Masuda, Klaus-Peter Knobeloch, Marco Prinz Institute of Neuropathology, Faculty of Medicine, University of Freiburg, Freiburg, Germany Maximilian Frosch, Takashi Shimizu, Emile Wogram, Lukas Amann, Maximilian Fliegauf, Marius Schwabenland, Chintan Chhatbar, Thomas Blank, Klaus-Peter Knobeloch & Marco Prinz Center for Mass Spectrometry and Optical Spectroscopy (CeMOS), Mannheim University of Applied Sciences, Mannheim, Germany Lars Gruber & Carsten Hopf Medical Faculty, Heidelberg University, Heidelberg, Germany Lars Gruber & Carsten Hopf Institute …
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