Mice B6.Cg-Gt(ROSA)26Sortm14(CAG-tdTomato)/Hze/J (iTdTomato) (007914), C57BL/6J (CD45.2) (000664) and B6.SJL-Ptprca Pepcb/BoyJ (CD45.1) (002014) mice were purchased from The Jackson Laboratory. Nestin–GFP mice48 were bred in our facility. Cdh5-creER, Cdh2-creER, Cxcl12fl/fl, Kitlfl/fl, Tpo−/− and Tg(Alb-Tpo) mice were provided by R. H. Adams, L. Li, T. Nagasawa, S. J. Morrison, F. J. de Sauvage and W. S. Alexander, respectively. Unless indicated otherwise, 8–10-week-old …
Read More »Haematopoietic stem cell number is not solely defined by niche availability
