Tag Archives: GutBrain

Summary: Researchers used AlphaFold3, the latest AI-based protein modeling system, to predict the structures of all 25 known human bitter taste receptors (T2Rs). Compared with AlphaFold2, AF3 consistently generated more accurate structural predictions when benchmarked against experimentally determined data. The study revealed strong structural similarities in intracellular regions of T2Rs, with significant variation in extracellular regions, explaining how different receptors …

There’s been a striking rise in disorders of gut-brain interaction (DGBI), including irritable bowel syndrome (IBS) and functional dyspepsia, since the COVID-19 pandemic, new survey data from the UK and the US showed. “Healthcare providers should recognize post-COVID DGBI as part of the long COVID spectrum. These post-COVID gut problems appear more severe and require more medical care than similar …

Key Questions Answered Q: What are disorders of gut-brain interaction (DGBIs)?A: DGBIs, such as irritable bowel syndrome (IBS) and functional dyspepsia, are conditions where the gut and brain fail to communicate properly, leading to chronic gastrointestinal symptoms without clear structural causes. Q: How much did these disorders increase after the pandemic?A: The study found a rise from 38.3% to 42.6% …