Tag Archives: genomes

Probe generation Probes, also referred to as ‘masks’ in the LexicHash paper, consist of a fixed number (m = 20,000 by default) of k-mers (k ≤ 32, k = 31 by default), which capture DNA sequences by prefix matching. A probe consists of two parts—the p-bp prefix and the remaining bases. To enable probes to match all possible reference and query sequences by prefix matching, all …

Ethics Statement All animal studies were approved by the Institutional Animal Care and Use Committee of Yale University. The tumor sizes in this study did not exceed the maximal tumor size (1 cm3) permitted by the institutional review board. Mouse and cell lines Mouse strains Mice were housed in a specific-pathogen-free facility with controlled temperature, humidity and day/night cycles and maintained …