Cell culture and cell lines The following CRC cell lines were obtained from the American Type Culture Collection (ATCC): HCT116 (ATCC, CCL-247), DLD1 (ATCC, CCL-221), RKO (ATCC, CRL-2577), HCT8 (ATCC, CCL-244), NCI-H508 (ATCC, CCL-253), Colo205 (ATCC, CCL-222), SW620 (ATCC, CCL-227), SW48 (ATCC, CCL-231) and HCT15 (ATCC, CCL-225). The DiFi, GP5D and HT55 cell lines were provided by J. Engelman, and …
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Dietary fibre-adapted gut microbiome clears dietary fructose and reverses hepatic steatosis
Mouse studies Animal studies followed protocols approved by the Institutional Animal Care and Use Committee of the University of California, Irvine (AUP-22-121). Male C57BL/6 mice (8 weeks old) were purchased from Jackson Laboratory. The duration of each experiment (for example, diet feeding) is indicated in the figure legends. In this study, only males were used because MASLD is more prevalent in …
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