Tag Archives: expansions

Hotspots of human mutation point to clonal expansions in spermatogonia

Hotspots of human mutation point to clonal expansions in spermatogonia

Lawson, A. R. J. et al. Somatic mutation and selection at population scale. Nature https://doi.org/10.1038/s41586-025-09584-w (2025). Maeda, H. & Kakiuchi, N. Clonal expansion in normal tissues. Cancer Sci. 115, 2117–2124 (2024). Article  CAS  PubMed  PubMed Central  Google Scholar  Bernstein, N. et al. Analysis of somatic mutations in whole blood from 200,618 individuals identifies pervasive positive selection and novel drivers of …

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