Tag Archives: exhaustion

Proteotoxic stress response drives T cell exhaustion and immune evasion

Proteotoxic stress response drives T cell exhaustion and immune evasion

Cell lines The MC38 cell line was purchased from Kerafast (ENH204-FP). The MB49 cell line was purchased from Sigma-Aldrich (SCC148). The HEK293T cell line was purchased from the American Type Culture Collection (CRL-3216). The MB49-gp33 cell line was shared by W. Cui (Northwestern University). The B16-OVA cell line was generated as previously described64 and shared by L. Deng (Memorial Sloan Kettering Cancer …

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Sony sues Tencent over Horizon Zero Dawn ‘clone’ – but the real issue is creative exhaustion

Sony sues Tencent over Horizon Zero Dawn ‘clone’ – but the real issue is creative exhaustion

Sony’s recent lawsuit against Tencent’s Polaris Quest studio over the game Light of Motiram, for similarities to the Horizon franchise, reads like a bizarre déjà vu moment for me, and I think for many gamers. And it speaks to a deeper issue with games and creativity. The claim? That Tencent’s new open-world, but unreleased, adventure appears to have heavily borrowed …

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