Tag Archives: DNA

Single-cell DNA methylome and 3D genome atlas of human subcutaneous adipose tissue

Single-cell DNA methylome and 3D genome atlas of human subcutaneous adipose tissue

Multimodal profiling of human SAT cell types To investigate the cell-type-level epigenomic landscape of human SAT, we profiled DNA methylation, chromatin conformation and gene expression on nuclei isolated from SAT biopsies from Finnish females (Fig. 1 and Supplementary Note 1.1). We used snm3C-seq to simultaneously profile single-cell-level DNA methylation and chromatin conformation of nuclei isolated from five SAT biopsies (see …

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Study Sheds Light on Dispersion of Languages, Ancient DNA

Study Sheds Light on Dispersion of Languages, Ancient DNA

The Language Velocity Field method helps understand the dispersion of language. Credit: Nature Communication Journal / CC BY 4.0 The groundbreaking Language Velocity Field (LVF) method is helping researchers trace dispersion patterns of languages, including Greek, across the world. The spatial evolution of languages can help deepen our understanding of people diffusion and cultural spread. The language velocity field estimation …

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Great white sharks have a DNA mystery science still can’t explain

Great white sharks have a DNA mystery science still can’t explain

White sharks exhibit stark differences between the DNA in their nuclei and the DNA in their mitochondria. Until now, scientists have pointed to the migration patterns of great whites to explain these differences. Scientists tested this theory in a new study by analyzing genetic differences between global white shark populations. In doing so, they discovered that great whites were restricted …

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Scientists may have found the tiny DNA switch that made us human

Scientists may have found the tiny DNA switch that made us human

Research from scientists at University of California San Diego School of Medicine have shed new light on an age-old question: what makes the human brain unique? The team’s discovery comes from their investigation of human-accelerated regions (HARs) — sections of the human genome that have accumulated an unusually high level of mutations as humans have evolved. There is a lot …

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