Tag Archives: clonal

Lawson, A. R. J. et al. Somatic mutation and selection at population scale. Nature https://doi.org/10.1038/s41586-025-09584-w (2025). Maeda, H. & Kakiuchi, N. Clonal expansion in normal tissues. Cancer Sci. 115, 2117–2124 (2024). Article  CAS  PubMed  PubMed Central  Google Scholar  Bernstein, N. et al. Analysis of somatic mutations in whole blood from 200,618 individuals identifies pervasive positive selection and novel drivers of …

Sample collection All enrolled patients were consented to an institutional biospecimen banking protocol and MSK-IMPACT testing42, and all analyses were performed per a biospecimen research protocol. Eligible patients had International Federation of Gynecology and Obstetrics stage III to IV HGSOC with diagnosis verified through clinicopathological review. All protocols were approved by the Institutional Review Board of the Memorial Sloan Kettering (MSK) Cancer …