Cancer cells mount an instant, energy-rich response to being physically squeezed, according to a study published in the journal Nature Communications. The surge of energy is the first reported instance of a defensive mechanism which helps the cells repair DNA damage and survive the crowded environments of the human body. The findings help explain how cancer cells survive complex mechanical …
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Scientists race to make ‘living’ computers powered by human cells
In the lab, FinalSpark’s cellular biologist Dr Flora Brozzi handed me a dish containing several small white orbs. Each little sphere is essentially a tiny, lab-grown mini-brain, made out of living stem cells which have been cultured to become clusters of neurons and supporting cells – these are the “organoids”. They are nowhere near the complexity of a human brain, …
Read More »Science news this week: Famed primatologist Jane Goodall dies, Iran sinks at an alarming rate, and scientists create human egg cells from skin
Leading our coverage this week was the passing of famed primatologist and conservationist Jane Goodall, who died of natural causes on Wednesday (Oct. 1) at age 91. Goodall became renowned for her pioneering studies of wild chimpanzees (Pan troglodytes) in Tanzania’s Gombe Stream National Park. She arrived at the park early in her career with no formal academic training in …
Read More »Scientists race to make ‘living’ computers powered by human cells
Zoe KleinmanTechnology editor BBC The building blocks for a biocomputer growing in a lab It may have its roots in science fiction, but a small number of researchers are making real progress trying to create computers out of living cells. Welcome to the weird world of biocomputing. Among those leading the way are a group of scientists in Switzerland, who …
Read More »Stroke Damage Reversed As Stem Cells Regrow the Brain
This image shows a coronal section through the mouse brain after stroke and neural stem cell transplantation. The dashed circle indicates the stroke area. The neurite projections of the transplanted human cells are stained in dark brown. Neurites extend locally into the cortex (CX) but also via the corpus callosum (CC) into the other brain hemisphere. Credit: University of Zurich …
Read More »Solid tumour CAR-T cells engineered with fusion proteins targeting PD-L1 for localized IL-12 delivery
Cell lines The mouse prostate cancer cell line PTEN−/− Kras (PTEN–Kras) derived from 10-week K-ras G12D;PTEN deletion mutant prostate cells was a kind gift from David Mulholland (The Icahn School of Medicine at Mount Sinai)42. The Ras/Myc transformed prostate cancer line, RM9, was a kind gift from Timothy C. Thompson (MD Anderson Cancer Centre) and has been previously described45. ID8, …
Read More »Fat Buildup in Brain Cells Could Provide New Target For Alzheimer’s Treatment : ScienceAlert
A new study suggests fat deposits in the brain may play a larger role in Alzheimer’s disease than previously thought. This could open a new avenue for potential treatment. Research has long focused on proteins found abnormally clumping in brains with neurodegeneration, but targeting these clumps has so far produced mixed results. So some researchers continue to search for missing …
Read More »Working Egg Cells Made Using DNA From Human Skin in World First : ScienceAlert
Scientists have created egg-like cells capable of fertilization using DNA from ordinary skin cells in what could be a major breakthrough for infertility research. Using a newly developed technique to remove excess chromosomes, a team led by clinical biologist Nuria Marti-Gutierrez of Oregon Health & Science University has created human eggs that can undergo successful fertilization and start to develop …
Read More »Scientists Made Human Eggs From Skin Cells and Used Them to Form Embryos
Mitinori Saitou at Kyoto University first documented in 2018 how his team turned human blood cells into stem cells, which they then transformed into human eggs, but they were too immature to be fertilized to make embryos. US startups Conception Biosciences, Ivy Natal, Gameto, and Ovelle Bio are all working on making eggs or sperm in a lab. But the …
Read More »Human skin cells are turned into eggs in fertility breakthrough | Science
Researchers have created human eggs from skin cells, potentially transforming IVF treatment for couples who have no other options. The work is at an early stage but if scientists can perfect the process it would provide genetically related eggs for women who are infertile because of older age, illness or medical treatment. The same procedure could be used to make …
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