Tag Archives: Cell

Neuronal activity-dependent mechanisms of small cell lung cancer pathogenesis

Neuronal activity-dependent mechanisms of small cell lung cancer pathogenesis

Mice and housing conditions All in vivo experiments were conducted in accordance with protocols approved by the Brigham and Women’s Hospital Institutional Animal Care and Use Committee (IACUC) and Stanford University IACUC. Mice were housed according to the standard guidelines with free access to food and water in a 12 h light:12 h dark cycle. For brain tumour allograft experiments, NSG mice …

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Functional synapses between neurons and small cell lung cancer

Functional synapses between neurons and small cell lung cancer

Mice This study was performed in accordance with FELASA recommendations and with European Union and German guidelines. The experiments were approved by the local ethics committee on animal experiments (Landesamt für Natur, Umwelt und Verbraucherschutz Nordrhein-Westfalen). Mice were housed in groups of up to five animals per cage and supplied with standard pellet food and water ad libitum with a …

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Newfound immune cell in mice hints at why inflammation spikes with old age

Newfound immune cell in mice hints at why inflammation spikes with old age

Macrophages, which hoover up pathogens, have been implicated in the chronic inflammation that sets in with the march of time.Credit: Science Photo Library A newly discovered type of immune cell found in fat tissue seems to contribute to the chronic inflammation associated with ageing, according to preliminary data from mice — but other immune cells in fat help to keep …

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More states are banning cell phones in schools : NPR

More states are banning cell phones in schools : NPR

As students across the country head back to class, one thing won’t be coming with many of them: their cell phones. This year more states than ever are banning students’ devices during school hours. In Texas, every public and charter school student will be without their phones during the school day this fall. Brigette Whaley, an associate professor of education …

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Maternal stress triggers early-life eczema through fetal mast cell programming

Maternal stress triggers early-life eczema through fetal mast cell programming

Mice Mice were bred and housed in the local animal facilities of the Centre Régional d’Exploration Fonctionnelle et de Ressources Expérimentales (CREFRE) in pathogen-free sanitary conditions, with free access to water and food, and were submitted to alternating cycles of 12 h of light and darkness at an ambient temperature of 22 °C. C57BL6j mice were purchased from Janvier Labs or Charles …

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Haematopoietic stem cell number is not solely defined by niche availability

Haematopoietic stem cell number is not solely defined by niche availability

Mice B6.Cg-Gt(ROSA)26Sortm14(CAG-tdTomato)/Hze/J (iTdTomato) (007914), C57BL/6J (CD45.2) (000664) and B6.SJL-Ptprca Pepcb/BoyJ (CD45.1) (002014) mice were purchased from The Jackson Laboratory. Nestin–GFP mice48 were bred in our facility. Cdh5-creER, Cdh2-creER, Cxcl12fl/fl, Kitlfl/fl, Tpo−/− and Tg(Alb-Tpo) mice were provided by R. H. Adams, L. Li, T. Nagasawa, S. J. Morrison, F. J. de Sauvage and W. S. Alexander, respectively. Unless indicated otherwise, 8–10-week-old …

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