These authors contributed equally: Chaoran Yin, Aleksandr Fedorov, Hongyan Guo Center for Immunology, Fox Chase Cancer Center, Philadelphia, PA, USA Chaoran Yin, Riley M. Williams, Avishekh Gautam, Sven Miller & Siddharth Balachandran Laboratory of Bioinformatics, Faculty of Computer Science, National Research University Higher School of Economics, 11 Pokrovsky Bulvar, Moscow, Russia Aleksandr Fedorov, Maria Poptsova & Alan Herbert Medical Research Council Translational Immune Discovery Unit, Medical Research Council …
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New Tool Reads DNA and RNA in a Single Cell, Unlocking Secrets of Disease – SciTechDaily
New Tool Reads DNA and RNA in a Single Cell, Unlocking Secrets of Disease SciTechDaily New Tool Enables Single-Cell Analysis of Specific Genetic Variants BIOENGINEER.ORG Scientists Develop New Single-Cell Sequencing Tool to Link Genetic Variants to Disease Insights SSBCrack New tool offers single-cell study of specific genetic variants Phys.org Source link
Read More »Bristol Myers Squibb Strengthens and Diversifies Cell Therapy Portfolio with Acquisition of Orbital Therapeutics – Business Wire
Bristol Myers Squibb Strengthens and Diversifies Cell Therapy Portfolio with Acquisition of Orbital Therapeutics Business Wire Bristol Myers to buy startup Orbital Therapeutics, building out cell therapy pipeline statnews.com BMS inks $1.5B in vivo CAR-T buyout to pull Orbital into its sphere of influence Fierce Biotech BMS Makes $1.5B Cell Therapy Play With Orbital Takeover BioSpace Bristol Myers joins in vivo CAR-T race with …
Read More »Spatial signatures for predicting immunotherapy outcomes using multi-omics in non-small cell lung cancer
Study population We studied three independent cohorts of patients with NSCLC who were treated with PD-1-based immunotherapies in the advanced or metastatic setting. The clinical characteristics of the cohorts are presented in Supplementary Tables 1 and 2. The first cohort, which served as the training cohort, was obtained from the Yale Cancer Center (New Haven). This cohort comprises 113 tissue …
Read More »Bristol Myers Squibb Strengthens and Diversifies Cell Therapy Portfolio with Acquisition of Orbital Therapeutics – Bristol Myers Squibb
Bristol Myers Squibb Strengthens and Diversifies Cell Therapy Portfolio with Acquisition of Orbital Therapeutics Bristol Myers SquibbView Full Coverage on Google News Source link
Read More »15-year-old daughter of Northern Virginia Del. Candi King dies after battle with sickle cell – InsideNoVa.com
15-year-old daughter of Northern Virginia Del. Candi King dies after battle with sickle cell InsideNoVa.com Colgan High School mourns death of Delegate Candi King’s daughter Potomac Local News Del. Candi Kings Daughter Dies After Sickle Cell Disease Battle Patch Del. Candi King’s daughter, 15, dies after battle with sickle cell disease Prince William Times What happened to Candi King’s daughter? Jay Jones’ post mourning …
Read More »Proteotoxic stress response drives T cell exhaustion and immune evasion
Cell lines The MC38 cell line was purchased from Kerafast (ENH204-FP). The MB49 cell line was purchased from Sigma-Aldrich (SCC148). The HEK293T cell line was purchased from the American Type Culture Collection (CRL-3216). The MB49-gp33 cell line was shared by W. Cui (Northwestern University). The B16-OVA cell line was generated as previously described64 and shared by L. Deng (Memorial Sloan Kettering Cancer …
Read More »The Biodiversity Cell Atlas: mapping the tree of life at cellular resolution
Goffeau, A. et al. Life with 6000 genes. Science 274, 546–567 (1996). Article ADS CAS PubMed Google Scholar C. elegans Sequencing Consortium.Genome sequence of the nematode C. elegans: a platform for investigating biology. Science 282, 2012–2018 (1998). Article ADS Google Scholar Initiative, T. A. G. Analysis of the genome sequence of the flowering plant Arabidopsis thaliana. Nature 408, 796–815 (2000). …
Read More »FDA unveils trio of new draft guidances to help cell and gene therapy developers
The FDA’s biologics center on Wednesday offered its latest recommendations to help streamline the development of novel cell and gene therapies for small patient populations … Sign up to read this article for free. Get free access to a limited number of articles, plus choose newsletters to get straight to your inbox. Source link
Read More »SPP1 is required for maintaining mesenchymal cell fate in pancreatic cancer
Blood samples from patients with pancreatic cancer Peripheral venous blood samples were collected from 26 patients with pancreatic cancer at the Seventh Affiliated Hospital of Sun Yat-sen University. Plasma was isolated from the collected blood samples, and plasma proteomic analysis was subsequently performed. Informed consent was obtained from all participants, and approvals were secured from the ethics board of the …
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