Rapper Gucci Mane’s newest release might be his most vulnerable yet. The Atlanta-based musician, promoting his third memoir, “Episode,” revealed to “The Breakfast Club” crew on Monday that he had been diagnosed with schizophrenia and bipolar disorder. He also went into detail about how he has learned to manage the mental health conditions, with a stern but helping hand from …
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McIntyre RS, Berk M, Brietzke E, Goldstein BI, López-Jaramillo C, Kessing LV, et al. Bipolar disorders. Lancet. 2020;396:1841–56. Article CAS PubMed Google Scholar Oliva V, Fico G, De Prisco M, Gonda X, Rosa AR, Vieta E. Bipolar disorders: an update on critical aspects. Lancet Reg Health Eur. 2024;48:101135. Article PubMed PubMed Central Google Scholar Léda-Rêgo G, Studart-Bottó P, Abbade P, …
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Summary: A large multicenter study has revealed that sex influences the course and characteristics of schizophrenia and bipolar disorder. Women with schizophrenia tended to begin treatment later, while men with schizophrenia had the highest rates of substance use. Individuals with bipolar disorder showed better functioning and cognitive performance than those with schizophrenia, with women scoring higher in verbal memory and …
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Summary: A new study uncovers a pancreas–hippocampus feedback loop that may help explain mood swings in bipolar disorder. Using patient-derived pancreatic islets, researchers found reduced insulin secretion linked to elevated RORβ, a bipolar risk gene. In mice, pancreatic RORβ overexpression caused depression-like behaviors during the day and mania-like behaviors at night through shifts in insulin release and hippocampal activity. The …
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Summary: Researchers have discovered hepatitis C virus (HCV) in the brain lining of individuals with schizophrenia and bipolar disorder, suggesting a possible link between infection and psychiatric symptoms. The study found HCV specifically in the choroid plexus, a structure producing cerebrospinal fluid, but not inside brain tissue itself. Analysis of medical records confirmed higher HCV prevalence in these disorders compared …
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