Tag Archives: Bipolar

Summary: A new study uncovers a pancreas–hippocampus feedback loop that may help explain mood swings in bipolar disorder. Using patient-derived pancreatic islets, researchers found reduced insulin secretion linked to elevated RORβ, a bipolar risk gene. In mice, pancreatic RORβ overexpression caused depression-like behaviors during the day and mania-like behaviors at night through shifts in insulin release and hippocampal activity. The …

Summary: Researchers have discovered hepatitis C virus (HCV) in the brain lining of individuals with schizophrenia and bipolar disorder, suggesting a possible link between infection and psychiatric symptoms. The study found HCV specifically in the choroid plexus, a structure producing cerebrospinal fluid, but not inside brain tissue itself. Analysis of medical records confirmed higher HCV prevalence in these disorders compared …