Ethics statement All animal experiments were approved by the UNC Institutional Animal Care and Use Committee (IACUC protocol ID: 24-029.0). Animal housing and feeding were centrally managed by the UNC Division of Comparative Medicine. Human blood was drawn by certified personnel at the UNC Center for AIDS Research and performed in compliance with ethics guidelines set forth by the institution’s …
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Credit: Chris Ratcliffe/Bloomberg via Getty Researchers are turning to artificial intelligence (AI) to help design the next generation of antibiotics to combat rising antimicrobial resistance. In minutes, AI can design thousands of chemical compounds with potential antibacterial properties, although there are hurdles to overcome before the first of these medicines can be tested in people. Last week, the US Centers …
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Ingredients of our daily diet – including caffeine – can influence the resistance of bacteria to antibiotics. This has been shown in a new study by a team of researchers at the Universities of Tübingen and Würzburg led by Professor Ana Rita Brochado. They discovered bacteria such as Escherichia coli (E. coli) orchestrate complex regulatory cascades to react to chemical …
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By EMILY JOSHU STERNE, US SENIOR HEALTH REPORTER Published: 00:30, 26 August 2025 | Updated: 00:44, 26 August 2025 It’s a drink most people enjoy every day. But consuming it while taking common antibiotics may raise the risk of being sickened by deadly bacteria. Researchers from three countries evaluated nearly 100 chemical substances and how they interacted with E. coli, a …
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A daily cup of coffee could be blunting the effects of certain antibiotic treatments, according to a new study analyzing the reaction of Escherichia coli bacteria to caffeine. The international team of researchers behind the study looked at 94 different chemical substances and how they changed E. coli: specifically, how they altered the systems that control what gets into and …
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A daily cup of coffee could be blunting the effects of certain antibiotic treatments, according to a new study analyzing the reaction of Escherichia coli bacteria to caffeine. The international team of researchers behind the study looked at 94 different chemical substances and how they changed E. coli: specifically, how they altered the systems that control what gets into and …
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In 1954, just a few years after the widespread introduction of antibiotics, doctors were already aware of the problem of resistance. Natural selection meant that using these new medicines gave an advantage to the microbes that could survive the assault – and a treatment that worked today could become ineffective tomorrow. A British doctor put the challenge in military terms: …
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AI drugs to tackle MRSA herald ‘second golden age in antibiotics’ The Times AI designs antibiotics for gonorrhoea and MRSA superbugs BBC Using generative AI, researchers design compounds that can kill drug-resistant bacteria MIT News Deep learning reveals antibiotics in the archaeal proteome Nature Superbugs Meet Their Match in Generative AI-Designed Drugs IEEE Spectrum Source link
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This could re-energise the drug pipeline just in time Could AI save us from the antibiotic apocalypse? That’s the hope from new research in which scientists designed novel drugs atom-by-atom to beat two notorious superbugs, including MRSA. Antibiotic resistance is a growing problem, causing the deaths of around five million people a year. Even routine operations could become life-threatening events …
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Getty Images Artificial intelligence has invented two new potential antibiotics that could kill drug-resistant gonorrhoea and MRSA, researchers have revealed. The drugs were designed atom-by-atom by the AI and killed the superbugs in laboratory and animal tests. The two compounds still need years of refinement and clinical trials before they could be prescribed. But the Massachusetts Institute of Technology (MIT) …
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