Study approval All participants provided written informed consent for participation in the study. Ethical approval was obtained from the Institutional Review Boards at La Jolla Institute for Immunology (protocol numbers VD-124, VD-118, VD-155 and VD-171), Massachusetts General Hospital (protocol number 2006P000982), Emory University (protocol number CR003-IRB00078771), University of California, Irvine (protocol number 20163191), National Institutes of Health (protocol number 17N0131), …
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