Study design The UKB is a prospective cohort study from the UK that contains more than 500,000 volunteers between 40 and 69 years of age at inclusion. The study design, sample characteristics and genotype data have been described elsewhere66,67. The UKB was approved by the National Research Ethics Service Committee North West Multi-Centre Haydock and all study procedures were performed in …
Read More »Tag Archives: allele
PICALM Alzheimer’s risk allele causes aberrant lipid droplets in microglia
Human iPS cell lines and culture The human iPS cell lines used for ATAC–seq (Supplementary Table 1) were derived at Rutgers University Cell and DNA Repository (RUCDR). The human iPS cell lines were generated using the Sendai virus method to ensure that they are integration-free and underwent the following quality-control procedures: immunofluorescence staining for pluripotency, mycoplasma contamination test, in-house RNA-seq-based …
Read More »