Summary: A new study demonstrates that long-term oral nicotine administration reprograms aging-related metabolism and slows motor decline in mice. By targeting the sphingolipid-energy axis, nicotine improved energy homeostasis, preserved gut microbial diversity, and supported neuromuscular resilience. Treated mice displayed a biologically younger phenotype based on integrated behavioral and metabolic analysis. The findings suggest nicotine’s molecular pathways may inspire the design …
Read More »Long-Term Nicotine Use Delays Aging-Linked Motor Decline
