Tag Archives: αsynuclein

Large-scale visualization of α-synuclein oligomers in Parkinson’s disease brain tissue

Large-scale visualization of α-synuclein oligomers in Parkinson’s disease brain tissue

Autofluorescence suppression and high-sensitivity microscopy reveals nanoscale assemblies in human brain tissue An overview of the ASA–PD pipeline is shown in Fig. 1. In brief, the aim is to capture spatial data over the entire scale of structure sizes most critical in PD, from individual cells to small aggregates (Fig. 1a). Detailed descriptions of the sample preparation steps are described …

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