The 2025 MLB playoffs are here, kicking off with the wild-card round — four best-of-three showdowns — all taking place at the site of the higher seeds.
The two division winners in each league with the best records (Milwaukee Brewers, Philadelphia Phillies, Toronto Blue Jays, Seattle Mariners) all get a chance to rest their regulars and set up their rotations for the next round, where they’ll square off with the winners of the series outlined below beginning Saturday, Oct. 4.
For more on the MLB playoffs, check out each team’s odds to win the World Series.
All odds accurate as of publish time. For more, go to ESPN BET Sportsbook. 
Cincinnati Reds at Los Angeles Dodgers
All games at Dodger Stadium, Los Angeles
Odds to win series: Dodgers (-250), Reds (+200)
Exact series result: Dodgers to sweep (+145), Dodgers in 3 (+225), Reds to sweep (+500), Reds in 3 (+400)
Game 1: Tuesday, Sept. 30 (9:08 p.m. ET)
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ML: Reds (+150), Dodgers (-180)
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Spread: Reds +1.5 (-155), Dodgers -1.5 (+130)
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Run total: Over 7.5 (+105), Under 7.5 (-125)
Game 2: Wednesday, Oct. 1 (9:08 p.m. ET)
*Game 3: Thursday, Oct. 2 (9:08 p.m. ET)
San Diego Padres at Chicago Cubs
All games at Wrigley Field, Chicago
Odds to win series: Cubs (-120), Padres (Even)
Exact series result: Cubs to sweep (+240), Cubs in 3 (+260), Padres to sweep (+300), Padres in 3 (+275)
Game 1: Tuesday, Sept. 30 (3:08 p.m. ET)
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ML: Padres (Even), Cubs (-120)
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Spread: Padres -1.5 (+170), Cubs +1.5 (-215)
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Run total: Over 7.5 (+115), Under 7.5 (-135)
Game 2: Wednesday, Oct. 1 (3:08 p.m. ET)
*Game 3: Thursday, Oct. 2 (3:08 p.m. ET)
Detroit Tigers at Cleveland Guardians
All games at Progressive Field, Cleveland
Odds to win series: Guardians (-110), Tigers (-110)
Exact series result: Guardians to sweep (+325), Guardians in 3 (+225), Tigers to sweep (+225), Tigers in 3 (+350)
Game 1: Tuesday, Sept. 30 (1:08 p.m. ET)
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ML: Tigers (-175), Guardians (+145)
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Spread: Tigers -1.5 (+115), Guardians +1.5 (-135)
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Run total: Over 6.5 (Even), Under 6.5 (-120)
Game 2: Wednesday, Oct. 1 (1:08 p.m. ET)
*Game 3: Thursday, Oct. 2 (1:08 p.m. ET)
Boston Red Sox at New York Yankees
All games at Yankee Stadium, New York
Odds to win series: Yankees (-185), Red Sox (+150)
Exact series result: Yankees to sweep (+185), Yankees in 3 (+225), Red Sox to sweep (+450), Red Sox in 3 (+325)
Game 1: Tuesday, Sept. 30 (6:08 p.m. ET)
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ML: Red Sox (+110), Yankees (-130)
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Spread: Red Sox +1.5 (-200), Yankees -1.5 (+165)
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Run total: Over 7.5 (+115), Under 7.5 (-135)
Game 2: Wednesday, Oct. 1 (6:08 p.m. ET)
*Game 3: Thursday, Oct. 2 (6:08 p.m. ET)
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