California health officials said an individual living in South Lake Tahoe has tested positive for the plague after recently camping in the area. According to officials with El Dorado County, the individual is recovering at home under the care of a medical professional. The South Lake Tahoe resident believes they may have been bitten by an infected flea while camping. …
Read More »Health
Thymic epithelial cells amplify epigenetic noise to promote immune tolerance
Mice The mice used in this study were housed in pathogen-free facilities at the University of Chicago and Stanford University. All mice were housed in positively pressurized, individually ventilated cage racks and changed in biological safety cabinets. Cage supplies were sanitized using hot water (82 °C). Bedding and shredded-paper enrichment were autoclaved and cages were provided with irradiated food. Reverse Osmosis …
Read More »South Lake Tahoe resident tests positive for plague
Facebook Tweet Email Link A Lake Tahoe area resident has tested positive for plague, California health officials said Tuesday. Officials said they believed the resident was infected after being bitten by an infected flea while camping in the South Lake Tahoe area. The person is recovering at home and under the care of medical professionals, El Dorado County officials said …
Read More »Hand, Foot and Mouth Disease (HFMD) cases grow as viral spread picks up across Philadelphia region
PHILADELPHIA (WPVI) — There has been an increase in cases of hand, foot, and mouth disease across the Philadelphia region. The uptick comes as kids, who are most susceptible to the virus, get ready to head back to school. “‘Tis the season for hand, foot and mouth disease. It tends to pop up at the end of summer and throughout …
Read More »What a 30-Year Study Just Found About Your French Fries and Diabetes – SciTechDaily
What a 30-Year Study Just Found About Your French Fries and Diabetes SciTechDaily Why Putin’s Russia spooks Western Europe Times of India Are potatoes good for you? Not french fries. USA Today Not All Potatoes Are Equal: French Fries Fuel Diabetes, But Mashed and Baked Potatoes Don’t ZME Science Are potatoes bad for type 2 diabetes? India Today Source link
Read More »Cancer-induced nerve injury promotes resistance to anti-PD-1 therapy
Clinical samples and cohorts Supplementary Table 10 summarizes the different clinical cohorts used in this Article, and presents the results of their relevant analysis. The full description of each cohort is depicted in the text and in Supplementary Table 10. Neoadjuvant anti-PD-1 cSCC clinical trial cohorts The clinical trials protocol, statistical analysis plan, and institutional review board approvals were previously …
Read More »SLC45A4 is a pain gene encoding a neuronal polyamine transporter
Study Population The UKB is a prospective cohort study that has collected extensive phenotypic and genetic data from approximately 500,000 participants across the United Kingdom21,45. All of the participants provided written informed consent. Phenotype description and assessment Phenotypes were defined using the ‘Experience of Pain’ UKB self-assessment questionnaire data under project ID 49572. This is part of the online UKB …
Read More »One Form of Exercise Improves Sleep The Most, Scientists Say : ScienceAlert
Rolling out a yoga mat and flowing with your breath could be one of the best exercises for improving sleep in the long run. A meta-analysis of 30 randomized controlled trials has revealed that regular, high-intensity yoga is more strongly associated with improved sleep than walking, resistance training, combination exercise, aerobic exercise, or traditional Chinese exercises, like qi gong and …
Read More »How wildfires hurt children’s brain development
In January, one of the deadliest wildfires in U.S. history ravaged several neighborhoods in Los Angeles County, including Pacific Palisades and Altadena. The immediate toll was staggering: at least 30 lives lost, more than 200,000 people evacuated, and more than 18,000 homes and structures destroyed. Moreover, a recent study estimated the fires were linked to more than 440 excess deaths in the region. Yet …
Read More »Fluorescent GLP1R/GIPR dual agonist probes reveal cell targets in the pancreas and brain
Glucagon-like peptide-1 (GLP1) and glucose-dependent insulinotropic polypeptide (GIP) potently amplify insulin secretion and influence satiety to reduce food intake1,2,3. Stabilized GLP1R agonists were approved for the treatment of type 2 diabetes in 2008 (ref. 4) and at higher doses for overweight and obesity in 2017 and 2018 (ref. 5). Less attention has been paid to the GIP axis, as multiple …
Read More »