Health

California resident tests positive for plague after camping in South Lake Tahoe

California resident tests positive for plague after camping in South Lake Tahoe

California health officials said an individual living in South Lake Tahoe has tested positive for the plague after recently camping in the area. According to officials with El Dorado County, the individual is recovering at home under the care of a medical professional. The South Lake Tahoe resident believes they may have been bitten by an infected flea while camping. …

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Thymic epithelial cells amplify epigenetic noise to promote immune tolerance

Thymic epithelial cells amplify epigenetic noise to promote immune tolerance

Mice The mice used in this study were housed in pathogen-free facilities at the University of Chicago and Stanford University. All mice were housed in positively pressurized, individually ventilated cage racks and changed in biological safety cabinets. Cage supplies were sanitized using hot water (82 °C). Bedding and shredded-paper enrichment were autoclaved and cages were provided with irradiated food. Reverse Osmosis …

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South Lake Tahoe resident tests positive for plague

South Lake Tahoe resident tests positive for plague

Facebook Tweet Email Link A Lake Tahoe area resident has tested positive for plague, California health officials said Tuesday. Officials said they believed the resident was infected after being bitten by an infected flea while camping in the South Lake Tahoe area. The person is recovering at home and under the care of medical professionals, El Dorado County officials said …

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What a 30-Year Study Just Found About Your French Fries and Diabetes – SciTechDaily

What a 30-Year Study Just Found About Your French Fries and Diabetes  SciTechDaily Why Putin’s Russia spooks Western Europe  Times of India Are potatoes good for you? Not french fries.  USA Today Not All Potatoes Are Equal: French Fries Fuel Diabetes, But Mashed and Baked Potatoes Don’t  ZME Science Are potatoes bad for type 2 diabetes?  India Today Source link

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Cancer-induced nerve injury promotes resistance to anti-PD-1 therapy

Cancer-induced nerve injury promotes resistance to anti-PD-1 therapy

Clinical samples and cohorts Supplementary Table 10 summarizes the different clinical cohorts used in this Article, and presents the results of their relevant analysis. The full description of each cohort is depicted in the text and in Supplementary Table 10. Neoadjuvant anti-PD-1 cSCC clinical trial cohorts The clinical trials protocol, statistical analysis plan, and institutional review board approvals were previously …

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SLC45A4 is a pain gene encoding a neuronal polyamine transporter

SLC45A4 is a pain gene encoding a neuronal polyamine transporter

Study Population The UKB is a prospective cohort study that has collected extensive phenotypic and genetic data from approximately 500,000 participants across the United Kingdom21,45. All of the participants provided written informed consent. Phenotype description and assessment Phenotypes were defined using the ‘Experience of Pain’ UKB self-assessment questionnaire data under project ID 49572. This is part of the online UKB …

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One Form of Exercise Improves Sleep The Most, Scientists Say : ScienceAlert

One Form of Exercise Improves Sleep The Most, Scientists Say : ScienceAlert

Rolling out a yoga mat and flowing with your breath could be one of the best exercises for improving sleep in the long run. A meta-analysis of 30 randomized controlled trials has revealed that regular, high-intensity yoga is more strongly associated with improved sleep than walking, resistance training, combination exercise, aerobic exercise, or traditional Chinese exercises, like qi gong and …

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How wildfires hurt children’s brain development

How wildfires hurt children’s brain development

In January, one of the deadliest wildfires in U.S. history ravaged several neighborhoods in Los Angeles County, including Pacific Palisades and Altadena. The immediate toll was staggering: at least 30 lives lost, more than 200,000 people evacuated, and more than 18,000 homes and structures destroyed. Moreover, a recent study estimated the fires were linked to more than 440 excess deaths in the region. Yet …

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Fluorescent GLP1R/GIPR dual agonist probes reveal cell targets in the pancreas and brain

Fluorescent GLP1R/GIPR dual agonist probes reveal cell targets in the pancreas and brain

Glucagon-like peptide-1 (GLP1) and glucose-dependent insulinotropic polypeptide (GIP) potently amplify insulin secretion and influence satiety to reduce food intake1,2,3. Stabilized GLP1R agonists were approved for the treatment of type 2 diabetes in 2008 (ref. 4) and at higher doses for overweight and obesity in 2017 and 2018 (ref. 5). Less attention has been paid to the GIP axis, as multiple …

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