Wednesday , 24 September 2025

NFL odds, lines, spreads: 2025 Week 4 picks, predictions from proven model: 5-way parlay pays almost 25-1

The Green Bay Packers look to rebound after suffering a stunning 13-10 defeat at Cleveland in Week 3. The Packers led 10-0 with four minutes to go before the Browns rallied for the win. Green Bay opened the season with two impressive wins over NFC contenders in Detroit and Washington, before suffering their first loss. The model is high on Green Bay (-7, 47.5) to cover against the Cowboys at Dallas. The Packers lead the all-time series 22-17, winning the past five meetings dating back to 2016.

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Jordan Love has had a solid season so far. Through three games, he has completed 53 of 78 passes (67.9%) for 663 yards and five touchdowns with one interception. He also has rushed 10 times for 34 yards, including a long run of 14. In the 27-18 Week 2 win over the Washington Commanders, he completed 19 of 31 passes (61.3%) for 292 yards and two touchdowns.

There are a number of intriguing matchups on the Week 4 NFL schedule, including Browns vs. Lions (-8.5), Commanders vs. Falcons (+2.5), Jets vs. Dolphins (-2.5), Titans vs. Texans (-7), Colts vs. Rams (-3.5) and Bears vs. Raiders (-1.5). Which other teams have value to include in Week 4 NFL parlay bets, and which side of the NFL odds should you target?

Before you lock in any NFL bets, make sure you see what SportsLine’s advanced computer model has to say. 

The model, which simulates every NFL game 10,000 times, is up well over $7,000 for $100 players on top-rated NFL picks since its inception. The model is on a sizzling 39-19 run on top-rated picks dating back to 2024. Anybody following could have seen HUGE returns!

The model has scoured the Week 4 NFL odds and locked in five confident NFL best bets. If you successfully parlay its sports betting picks, you’d be looking at a massive payout of around 24-1. 

One pick we’ll give away: The model is backing the Texans (-7) to cover against the Titans well over 50% of the time.

The model is also backing a surprising underdog that it says will not only cover, but win outright! You ABSOLUTELY NEED to see its NFL picks for every game before you make any NFL bets of your own!

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